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KMID : 1137820110320010045
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의공학회지
2011 Volume.32 No. 1 p.45 ~ p.54
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Development of a Low-Noise Amplifier System for Nerve Cuff Electrodes
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Song Kang-Il
Chu Jun-Uk
Francis Suh Jun-Kyo
Choe Gwi-Won
Yoo Sun-Kook
Youn In-Chan
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Abstract
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Cuff electrodes have a benefit for chronic electroneurogram(ENG) recording while minimizing nerve damage. However, the ENG signals are usually contaminated by electromyogram(EMG) activity from the surrounding muscle, the thermal noise generated within the source resistance, and the electric noise generated primarily at the first stage of the amplifier. This paper proposes a new cuff electrode to reduce the interference of EMG signals. An additional middle electrode was placed at the center of cuff electrode. As a result, the proposed cuff electrode achieved a higher signal-to-interference ratio compared to the conventional tripolar cuff. The cuff electrode was then assembled together with closure, headstage, and hermetic case including electronic circuits. This paper also presents a lownoise amplifier system to improve signal-to-noise ratio. The circuit was designed based on the noise analysis to minimize the electronic noise. The result shows that the total noise of the amplifier was below for a cuff impedance of and the common-mode rejection ratio was 115 dB at 1 kHz. In the current study, the performance of nerve cuff electrode system was evaluated by monitoring afferent nerve signals under mechanical stimuli in a rat animal model.
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KEYWORD
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Peripheral nerve signal, Nerve cuff electrode, Low-noise amplifier, Sciatic nerve
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